I did this with the shell command in a commandline environment. I didn't try this out with a webserver, but you could give it a shot.
set wShell = server.createObject(wScript.shell)
wShell.run("%comspec% /c run notepad.exe ")
...you need to preface the DOS command with "%comspec% /c"
The server creates an instance of the wscript shell object. It then sends an environmental variable to command.exe. The DOS command is "run notepad.exe" .You will probably have to put the path in front of notepad.exe however.
I hope this helps.